CMC Reg Affairs

We are specialists in CMC regulatory affairs of both APIs and drug products.
Territories covered: USA, EU, UK, Canada, Australia, Japan, Brazil, and Mexico. Please get in touch to discuss about our pharmaceutical services in other markets.

Our team can support you in the following:

API regulatory Affairs

  • Regulatory dossier (US DMF, ASMF, CEP, eCTD) authoring for new products
  • Life-cycle maintenance
  • Regulatory strategy
  • Change-control assessment
  • DMF updates and annual reports
  • Gap analysis
  • CEP variations
  • Responding to deficiency letters from regulatory authorities

Drug Product Regulatory Affairs

  • Regulatory dossier (US, EU and eCTD) authoring for new products
  • Life-cycle maintenance: Variations (EU and US) and annual updates
  • Regulatory strategy
  • Change-control assessment
  • USFDA: Abbreviated New Drug applications (ANDA)
  • EU: National, Mutual Recognition Procedure (MRP), Decentralised Procedure (DCP) and Centralised Procedure (CP)
  • Gap analysis
  • Responding to request for information (RFI) from regulatory authorities

Biosimilars

Information to follow

Medical Devices

  • Support for approval of new product
  • Review of EU technical files
  • GAP analysis
  • IFU – Instructions for use
  • Support MDR and IVDR regulation
  • Labelling compliance
  • UDI – Unique Device Identification
  • Support for UKCA marking
  • Preparation and management of technical documentation according to GSPR (General Safety and Performance Requirements)
  • EU authorised representative service